BDBM481781 6-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydro-1,3,4- oxadiazol-2-yl]methyl)-1- methyl-7-oxo- 1H,3aH,6H,7H,7aH- pyrazolo[4,3-d]pyrimidine- 3-carbonitrile::US10913742, Example 23

SMILES Cn1nc(C#N)c2ncn(Cc3nn(CCc4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=PVJKXHORDRYXDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481781   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481781(6-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydr...)
Affinity DataIC50:  100nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent