BDBM481781 6-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydro-1,3,4- oxadiazol-2-yl]methyl)-1- methyl-7-oxo- 1H,3aH,6H,7H,7aH- pyrazolo[4,3-d]pyrimidine- 3-carbonitrile::US10913742, Example 23
SMILES Cn1nc(C#N)c2ncn(Cc3nn(CCc4ccc(Cl)cc4)c(=O)o3)c(=O)c12
InChI Key InChIKey=PVJKXHORDRYXDV-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481781
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 100nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair