BDBM481818 3-[[4-[3-fluoro-3-(4- fluorophenyl)cyclobutyl]-5- oxo-1,3,4-oxadiazol-2- yl]methyl]-5-methyl-4-oxo- pyrido[2,3-d]pyrimidine-7- carbonitrile::US10913742, Example 61
SMILES Cc1cc(nc2ncn(Cc3nn([C@H]4C[C@@](F)(C4)c4ccc(F)cc4)c(=O)o3)c(=O)c12)C#N
InChI Key InChIKey=OXBAGLABLAJOLY-MIRVZWSXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481818
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 11.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair