BDBM481823 5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]-3-[3- (6-quinolyl)cyclobutyl]-1,3,4- oxadiazol-2-one::US10913742, Example 66
SMILES Cc1ccnc2ncn(Cc3nn([C@H]4C[C@@H](C4)c4ccc5ncccc5c4)c(=O)o3)c(=O)c12
InChI Key InChIKey=DHGUOHDVYXFMFQ-IYARVYRRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481823
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 12.5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair