BDBM481836 5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]-3- [rac-(2R)-2-[4- (difluoromethoxy)phenyl]-2- fluoro-ethyl]-1,3,4-oxadiazol- 2-one::US10913742, Example 80

SMILES Cc1ccnc2ncn(Cc3nn(C[C@H](F)c4ccc(OC(F)F)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=IGOGZZUWJQNUTI-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481836   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481836(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50:  11.9nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent