BDBM481850 US10913742, Example 94::trans-3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-5-[(4- oxopyrido[2,3-d]pyrimidin-3- yl)methyl]-1,3,4-oxadiazol- 2-one

SMILES F[C@@]1(C[C@@H](C1)n1nc(Cn2cnc3ncccc3c2=O)oc1=O)c1ccc(Cl)cc1

InChI Key InChIKey=GNNUMLYAKUEIDE-LDTOLXSISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481850   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481850(US10913742, Example 94 | trans-3-[3-(4-chloropheny...)
Affinity DataIC50:  16.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent