BDBM481855 3-[3-fluoro-3-[4- (trifluoromethyl)phenyl] cyclobutyl]-5-[(5-methyl-4-oxo- pyrido[2,3-d]pyrimidin-3 yl)methyl]-1,3,4-oxadiazol- 2-one::US10913742, Example 99

SMILES Cc1ccnc2ncn(Cc3nn([C@H]4C[C@](F)(C4)c4ccc(cc4)C(F)(F)F)c(=O)o3)c(=O)c12

InChI Key InChIKey=GKROVECUBNNFBQ-WEHONNDLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481855   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481855(3-[3-fluoro-3-[4- (trifluoromethyl)phenyl] cyclobu...)
Affinity DataIC50:  57.3nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent