BDBM481860 US10913742, Example 105::trans-3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-5-[(7-methyl- 6-oxo-purin-1-yl)methyl]-1,3,4- oxadiazol-2-one
SMILES Cn1cnc2ncn(Cc3nn([C@H]4C[C@@](F)(C4)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12
InChI Key InChIKey=HBROHCUKWVIOIZ-XVDXERDNSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481860
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 64nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair