BDBM482105 US10913753, Compound I-172::US20230365583, Compound 23
SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)C1CC2CCC(C1)N2
InChI Key InChIKey=CRTNETOPEFHLTG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 482105
Affinity DataIC50: <200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:USP28 (at 1 nM) was pre-incubated with different concentrations of inhibitors or DMSO as a control in 50 mM Tris pH 8, 50 mM NaCl, 0.002% Tween-20, 5...More data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair