BDBM482850 N5- (cyclopropylsulfonyl)- 1-(2-((2R,4R)- 4-fluoro-2-((R)-1- hydroxy-2-(6- methylpyridin-2-yl) ethyl)pyrrolidin-1- yl)-2-oxoethyl)- 1H-indole-3,5- dicarboxamide::US10919884, Cmp No. 6::US11649229, Cmp No. 6

SMILES Cc1cccc(CC(O)[C@H]2C[C@@H](F)CN2C(=O)Cn2cc(C(N)=O)c3cc(ccc23)C(=O)NS(=O)(=O)C2CC2)n1

InChI Key InChIKey=RHJIVCKCZJGUTH-KWTFHKEJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482850   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482850(N5- (cyclopropylsulfonyl)- 1-(2-((2R,4R)- 4-fluoro...)
Affinity DataIC50:  5.50E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482850(N5- (cyclopropylsulfonyl)- 1-(2-((2R,4R)- 4-fluoro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent