BDBM483558 US10927086, Example 30::propoxy)-1,2,5-oxadiazole-3-carboximidamide

SMILES C[S@@](=N)(=O)CCCOc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=ZKCFCHCBOHTDBD-GWQKEKGPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483558   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483558(US10927086, Example 30 | propoxy)-1,2,5-oxadiazole...)
Affinity DataIC50:  231nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent