BDBM483669 1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (methyl)amino)- piperidine-1- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 81::US11655217, Example 81

SMILES CN(Cc1cc(Cl)ccc1C(F)(F)F)C1CCN(CC1)C(=O)n1ccc(n1)C(O)=O

InChI Key InChIKey=JEMFJPUDTAMBJN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483669   

TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483669(1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (me...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483669(1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (me...)
Affinity DataIC50:  550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483669(1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (me...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483669(1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (me...)
Affinity DataIC50:  550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent