BDBM483693 4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thiophen-2- yl)methyl)-1,8- diazaspiro[4.5]- decane-8- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 139::US11655217, Example 139

SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCC2(CCCN2Cc2cc3ccc(cc3s2)C(F)(F)F)CC1

InChI Key InChIKey=ULXYVURIRYFFRS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483693   

TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483693(4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thio...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483693(4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thio...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483693(4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thio...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483693(4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thio...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent