BDBM483759 1-(trans-5-(3- methyl-4- (trifluoromethyl)- phenoxy)- octahydrocyclopenta- [c]pyrrole-2- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 254::US11655217, Example 254

SMILES Cc1cc(O[C@@H]2C[C@H]3CN(C[C@H]3C2)C(=O)n2ccc(n2)C(O)=O)ccc1C(F)(F)F

InChI Key InChIKey=IRBCDPFTHWRMSE-NHAGDIPZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483759   

TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483759(1-(trans-5-(3- methyl-4- (trifluoromethyl)- phenox...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483759(1-(trans-5-(3- methyl-4- (trifluoromethyl)- phenox...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent