BDBM483868 1-(7-(2,5- dichlorobenzyl)-2,7- diazaspiro[4.4]- nonane-2-carbonyl)-N- methyl-1H-pyrazole-3- carboxamide::US10927105, Ex 428::US11655217, Example 428

SMILES CNC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3cc(Cl)ccc3Cl)C2)C1

InChI Key InChIKey=CIXPVOMCOXYVAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483868   

TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483868(1-(7-(2,5- dichlorobenzyl)-2,7- diazaspiro[4.4]- n...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483868(1-(7-(2,5- dichlorobenzyl)-2,7- diazaspiro[4.4]- n...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent