BDBM484296 (R)-1-(3-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)-5- propoxyimidazo[1,5-a]pyrazin-3- yl)pyrrolidin-1-yl)prop-2-en-1-one::US10933063, Compound 95::US11554118, Compound 95

SMILES CCCOc1cncc2c(nc([C@@H]3CCN(C3)C(=O)C=C)n12)-c1ccc(Oc2cccc(OC)c2F)cc1

InChI Key InChIKey=XQYQCTODHOZZCL-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484296   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484296((R)-1-(3-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)...)
Affinity DataIC50: <10nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484296((R)-1-(3-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)...)
Affinity DataIC50:  30nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent