BDBM484448 US10934285, Example 34

SMILES CC1(CN)CCN(CC1)c1nnc(Sc2cccc(NC(=O)c3c(O)nc4cnccn4c3=O)c2Cl)c(N)n1

InChI Key InChIKey=XPUOOXTUODGYTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484448   

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484448(US10934285, Example 34)
Affinity DataIC50:  14nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent