BDBM484460 N-(3-((2-(4-Amino-4-methylpiperidin-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)thio)phenyl)-4-hydroxy-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide::US10934285, Example 46
SMILES CC1(N)CCN(CC1)c1nc2ccc(Sc3cccc(NC(=O)C4=C(O)CN(C4=O)c4ccccc4)c3)nc2[nH]1
InChI Key InChIKey=ASDMJNDNXWLXNY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 484460
Affinity DataIC50: 70nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair