BDBM484476 US10934285, Example 63

SMILES CCC1N(C(=O)C(C(=O)Nc2cccc(Sc3ccc4nc([nH]c4n3)N3CCCCC3)c2Cl)=C1O)c1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484476   

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484476(US10934285, Example 63)
Affinity DataIC50:  52nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent