BDBM485532 N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(4-((6-methylpyridin-2- yl)oxy)phenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide::US10934310, Ex # 369::US11319329, Ex # 369

SMILES Cc1cccc(Oc2ccc(cc2)-n2c3ccnc4sc(C(=O)N[C@@H]5CCC[C@@H]5NC(=O)C=C)c([nH]c2=O)c34)n1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485532   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM485532(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(4-((6-methy...)
Affinity DataIC50:  8.71nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM485532(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(4-((6-methy...)
Affinity DataIC50:  8.71nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent