BDBM485679 US10941129, Example 2

SMILES OC[C@H](NCc1ccc(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1cccc(c1)C#N)C(O)=O

InChI Key InChIKey=DYDQRLKTIGIFNQ-NDEPHWFRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485679   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute Of Materia Medica, Chinese Academy Of Medical Sciences

US Patent
LigandPNGBDBM485679(US10941129, Example 2)
Affinity DataIC50:  29.4nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent