BDBM485693 N-(tetrahydro-2H-pyran-4-yl)-4-(2-bromo-3-phenylbenzyloxy)-2-(3-cyanobenzyloxy) benzylamine::US10941129, Example 9

SMILES Brc1c(COc2ccc(CNC3CCOCC3)c(OCc3cccc(c3)C#N)c2)cccc1-c1ccccc1

InChI Key InChIKey=WXJWMMOWQMYFEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485693   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute Of Materia Medica, Chinese Academy Of Medical Sciences

US Patent
LigandPNGBDBM485693(N-(tetrahydro-2H-pyran-4-yl)-4-(2-bromo-3-phenylbe...)
Affinity DataIC50:  788nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent