BDBM485778 (S)—N-Methyl-3-(quinolin-5-yloxy)-3-(thiazol-2-yl)propan-1-amine and (R)—N-methyl-3-(quinolin-5-yloxy)-3-(thiazol-2-yl)propan-1-amine::US10941138, Example 76::US10941138, Example 77
SMILES CNCC[C@H](Oc1cccc2ncccc12)c1nccs1
InChI Key InChIKey=BYXCBFNAGGVRKV-HNNXBMFYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 485778
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals
US Patent
Esteve Pharmaceuticals
US Patent
Affinity DataKi: 300nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals
US Patent
Esteve Pharmaceuticals
US Patent
Affinity DataKi: 1.75E+3nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair