BDBM486068 US10947210, Compound 06-7C

SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=NVGMUTUBIJXDMN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486068   

TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM486068(US10947210, Compound 06-7C)
Affinity DataEC50: <100nMAssay Description:HCV replicon assay is based on the luciferase reporter cell line (Huh-luc/neo-ET). This reporter cell line is a human liver carcinoma cell line (Huh-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM486068(US10947210, Compound 06-7C)
Affinity DataIC50:  550nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent