BDBM486149 US10947210, Compound 09-14F

SMILES CNC(=O)c1c(oc2cc(N(CC(=O)NC(C)C(=O)NCc3cccc(c3)C(=O)\C=C(/O)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=IWCAIDFQFRBYID-MWLSYYOVSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486149   

TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM486149(US10947210, Compound 09-14F)
Affinity DataEC50:  550nMAssay Description:HCV replicon assay is based on the luciferase reporter cell line (Huh-luc/neo-ET). This reporter cell line is a human liver carcinoma cell line (Huh-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM486149(US10947210, Compound 09-14F)
Affinity DataIC50: >1.00E+3nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent