BDBM486364 (S)-3-(2-chlorophenyl)-1-(4- fluorophenyl)-N-(1-(6- (trifluoromethyl)pyridin-3-yl)ethyl)- 1H-indole-6-carboxamide::US10947222, Example 6

SMILES C[C@H](NC(=O)c1ccc2c(cn(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=GQRKMAWMERSXSW-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486364   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486364((S)-3-(2-chlorophenyl)-1-(4- fluorophenyl)-N-(1-(6...)
Affinity DataIC50:  476nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent