BDBM486371 3-(2-chlorophenyl)-2-cyano-1-(4- fluorophenyl)-N-(3-methyl-1,1- dioxidotetrahydrothiophen-3-yl)-1H- indole-6-carboxamide (Enantiomer B)::US10947222, Example 9-B

SMILES C[C@@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(c(C#N)n(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl

InChI Key InChIKey=IXIVURNZQDPZNJ-MHZLTWQESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486371   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486371(3-(2-chlorophenyl)-2-cyano-1-(4- fluorophenyl)-N-(...)
Affinity DataIC50:  235nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent