BDBM486421 N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluorophenyl)-3- pyrimidin-5-yl-1H-indole-6- carboxamide (racemic)::US10947222, Example 50

SMILES Fc1ccc(cc1)-n1cc(-c2cncnc2)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1

InChI Key InChIKey=FFMGLTZPVKSSAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486421   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486421(N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluor...)
Affinity DataIC50:  321nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent