BDBM486454 Synthetic Method #1::US10947226, Example 1

SMILES CN1c2ccc(=O)n(C)c2CC[C@H](NC(=O)c2ncn(Cc3ccccc3)n2)C1=O

InChI Key InChIKey=IIHOSZGWHGQGIR-HNNXBMFYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486454   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM486454(Synthetic Method #1 | US10947226, Example 1)
Affinity DataKi:  233nMAssay Description:Enzyme assay: The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent