BDBM486543 US10947251, Example 20
SMILES COc1cc(cc(F)c1N1[C@H]2CCN(C[C@@H]2OCC1=O)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C(F)(F)F
InChI Key InChIKey=MGYYQTMVKDWCEY-ICSRJNTNSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486543
Affinity DataIC50: 39.8nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Heterologously Express hNav1.7 and the β1 SubunitPreparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant...More data for this Ligand-Target Pair