BDBM486910 US10947252, Example 377::US11427601, Example 377

SMILES Cc1ccc(cc1CN1CC2(CCOCC2)Oc2nc(OCCN3CCCC3)c(C)cc2S1(=O)=O)[C@@H](c1ccn2c(nnc2c1C)C(F)F)C(C)(C)C(O)=O

InChI Key InChIKey=JUOUKRLLZCMBJP-HKBQPEDESA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486910   

TargetKelch-like ECH-associated protein 1 [321-624](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM486910(US10947252, Example 377 | US11427601, Example 377)
Affinity DataKd: <1nMAssay Description:The details of the KEAP1 KELCH ThermoFluorŪ Assay Construct are as follows: Kelch domain of human KEAP 1 (321-624 aa) was used in the assay. The prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM486910(US10947252, Example 377 | US11427601, Example 377)
Affinity DataKd: <1nMAssay Description:The ThermoFluorŪ is a fluorescence based assay (Tf) that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent