BDBM486965 US10947252, Example 445::US11427601, Example 445

SMILES Cc1cc2cc([C@H](CC(O)=O)c3ccc(C)c(CN4C[C@H]5CCCCN5c5ncccc5S4(=O)=O)c3)n(C)c2nn1

InChI Key InChIKey=IMRNAESQPBZZKY-JWQCQUIFSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486965   

TargetKelch-like ECH-associated protein 1 [321-624](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM486965(US10947252, Example 445 | US11427601, Example 445)
Affinity DataKd: <1nMAssay Description:The details of the KEAP1 KELCH ThermoFluorŪ Assay Construct are as follows: Kelch domain of human KEAP 1 (321-624 aa) was used in the assay. The prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM486965(US10947252, Example 445 | US11427601, Example 445)
Affinity DataKd: <1nMAssay Description:The ThermoFluorŪ is a fluorescence based assay (Tf) that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent