BDBM488170 US10954225, Example 15,P-1::US10954225, Example 15,P-2

SMILES Oc1ccc(cc1)C1CCN(C[C@H]1F)C1CCON(Cc2ccc(F)cc2)C1=O

InChI Key InChIKey=NXDMPSWVSBJLBA-NYLDSWQDSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488170   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM488170(US10954225, Example 15,P-1 | US10954225, Example 1...)
Affinity DataKi:  12.5nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM488170(US10954225, Example 15,P-1 | US10954225, Example 1...)
Affinity DataKi:  393nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent