BDBM49636 (E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-propen-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-prop-2-en-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-ylprop-2-en-1-one::(E)-1-indolin-1-yl-3-(2-thienyl)prop-2-en-1-one::1-[3-(2-thienyl)acryloyl]indoline::MLS000678854::SMR000269910::cid_885474

SMILES O=C(\C=C\c1cccs1)N1CCc2ccccc12

InChI Key InChIKey=AGFMCRQYCDIVNO-BQYQJAHWSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 49636   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49636((E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-pr...)
Affinity DataEC50:  356nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49636((E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-pr...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49636((E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-pr...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49636((E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-pr...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49636((E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-pr...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay