BDBM50000214 CHEMBL337862

SMILES C(Nc1ccccc1-c1ccccc1)C1=NCCN1

InChI Key InChIKey=RJDGUOVDCSODNG-UHFFFAOYSA-N

Data  4 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50000214   

TargetNischarin(RAT)TBA
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataKi:  0.933nMAssay Description:Binding affinity to I1 imidazoline binding site in Rattus norvegicus (rat) PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNischarin(RAT)TBA
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-p-iodoclonidine from I1 receptor imidazoline binding site in Sprague-Dawley rat kidney cell membranes after 30 mins by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A/B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataKi:  813nMAssay Description:Displacement of [3H]idazoxan from imidazoline receptor I-2 binding sites in rabbit kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human alpha2a-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50:  148nMAssay Description:Agonist activity at human alpha2c-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50:  7.90nMAssay Description:Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50:  794nMAssay Description:Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50000214(CHEMBL337862)
Affinity DataEC50:  955nMAssay Description:Agonist activity at human alpha2b-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed