BDBM50004426 CHEMBL3238465

SMILES Cc1cccc(NC(=O)c2cc(cc(c2)[N+]([O-])=O)[N+]([O-])=O)c1

InChI Key InChIKey=UZSXNOWPVBPHDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004426   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50004426(CHEMBL3238465)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50004426(CHEMBL3238465)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed