BDBM50004801 3-(3-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL137648

SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1cccc(F)c1)C2=O)c1ccccc1

InChI Key InChIKey=DXZKTRNEOISOCA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004801   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004801(3-(3-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-b...)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [3H]-spiperone from dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004801(3-(3-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-b...)
Affinity DataKi:  5.30nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed