BDBM50004817 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-methyl-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135832

SMILES Cc1ccccc1CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O

InChI Key InChIKey=MRXPMPSDRAGQAV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004817   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004817(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-methyl-be...)
Affinity DataKi:  0.0330nMAssay Description:Displacement of [3H]-spiperone from dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004817(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-methyl-be...)
Affinity DataKi:  9.60nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed