BDBM50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide

SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC

InChI Key InChIKey=WAOQONBSWFLFPE-VIFPVBQESA-N

Data  65 KI  14 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 82 hits for monomerid = 50005118   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.10nMAssay Description:Inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.10nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.80nMAssay Description:In vitro binding affinity against dopamine receptor D2 in rat striata; value ranges from 1.8-3.0 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.99nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Sprague-Dawley rat striatal membranes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  3.70nMAssay Description:Compound was measured for its ability to compete with [3H]spiperone binding to the human Dopamine receptor D3 transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  5.10nMAssay Description:In vitro inhibition of [3H]-Spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes (using L-tartrate salt of authentic rac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  8.70nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  9.30nMAssay Description:Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  9.5nMAssay Description:Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  10.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  13nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  13nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]spiperone from dopamine D3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]spiperone from dopamine D2long receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  26nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]spiperone from dopamine D2short receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  32nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  134nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  237nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  620nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  620nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Reading

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  880nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Astra LÄKemedel

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  902nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.34E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.86E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.87E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
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