BDBM50006459 CHEMBL304995::[3-(5,7-Difluoro-benzothiazol-2-ylmethyl)-4-oxo-3,4,5,6,7,8-hexahydro-phthalazin-1-yl]-acetic acid

SMILES OC(=O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c2CCCCc12

InChI Key InChIKey=QJZIGPVOTXIJRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006459   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006459(CHEMBL304995 | [3-(5,7-Difluoro-benzothiazol-2-ylm...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed