BDBM50008977 (8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-acetonitrie::(8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-acetonitrile::2-(8-(benzyloxy)-2-methylimidazo[1,2-a]pyridin-3-yl)acetonitrile::CHEMBL47529
SMILES Cc1nc2c(OCc3ccccc3)cccn2c1CC#N
InChI Key InChIKey=PYKJFEPAUKAXNN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50008977
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research
Curated by ChEMBL
Smith Kline & French Research
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair