BDBM50014549 CHEMBL3261480::US9045501, 4

SMILES Cc1cn2CCN([C@@H]3CN4CCC3CC4)C(=O)c3cc(Cl)cc1c23

InChI Key InChIKey=VVNHBZRFRXWLFQ-QGZVFWFLSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014549   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nM ΔG°:  -13.2kcal/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed