BDBM50014707 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoylamino}-pentanedioic acid::CHEMBL431359
SMILES CC(Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O)c1cnc2nc(N)nc(N)c2n1
InChI Key InChIKey=SEJWECNFKLVVFC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50014707
Affinity DataKi: 0.00520nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration of the compound inhibiting thymidylate synthase enzyme of L. caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting GAR transformylase enzyme of L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting AICAR formyltransferase enzyme of L. caseiMore data for this Ligand-Target Pair