BDBM50014843 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propyl]-formyl-amino}-benzoylamino)-pentanedioic acid::CHEMBL152172

SMILES Nc1nc(N)c(CCCN(C=O)c2ccc(cc2)C(=O)NC(CCC(O)=O)C(O)=O)c(=O)[nH]1

InChI Key InChIKey=KOOBXXUWGKUQCV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014843   

TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)
Affinity DataIC50:  5.74E+5nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against L cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed