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BDBM50016706 CHEMBL63139::Octahydro-indolizine-1,2,8-triol::Swainsonine::TRIDOLGOSIR::Tridolgosir

SMILES: [H][C@@]12[C@H](O)[C@H](O)CN1CCC[C@H]2O

InChI Key: InChIKey=FXUAIOOAOAVCGD-RYVOCIFZSA-N

Data: 1 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016706   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-mannosidase 2C1


(Rattus norvegicus)
BDBM50016706
PNG
(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Show SMILES O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O
Show InChI InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6?,7-,8?/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a 1.75E+3n/an/an/an/an/an/a



CSIRO Division of Chemicals and Polymers

Curated by ChEMBL


Assay Description
Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)


J Med Chem 32: 2084-9 (1989)


Article DOI: 10.1021/jm00129a011
BindingDB Entry DOI: 10.7270/Q2TQ6246
More data for this
Ligand-Target Pair