BDBM50016991 7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-benzofuran-4-ol::CHEMBL280055

SMILES CCCc1cc(F)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O

InChI Key InChIKey=NDHLVTVXZUEGII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016991   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016991(7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  129nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016991(7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  7nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed