BDBM50020846 8-(3-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione::CHEMBL11054

SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cccc(O)c1

InChI Key InChIKey=UZPPSCQEEUUJSB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020846   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020846(8-(3-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  340nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50020846(8-(3-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50020846(8-(3-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataIC50:  6nMAssay Description:Binding affinity against bovine brain adenosine A1 receptor by using N6-[3H]- cyclohexyladenosineChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed