BDBM50021404 CHEMBL3289873

SMILES COc1cccc(-c2cc(C)c(s2)C(=O)N(C)Cc2cccc(O)c2)c1F

InChI Key InChIKey=JVVLBENNFHXWCI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021404   

TargetEstradiol 17-beta-dehydrogenase 2(Mus musculus)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021404(CHEMBL3289873)
Affinity DataIC50:  54nMAssay Description:Inhibition of mouse liver 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021404(CHEMBL3289873)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of human placental 17beta-HSD1 cytosolic fraction using tritiated estrone as substrate assessed as formation of estradiol by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021404(CHEMBL3289873)
Affinity DataIC50:  235nMAssay Description:Inhibition of human placental 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed