BDBM50023384 CHEMBL3325610::US9242957, QJ-II-203

SMILES NC[C@@H](COCc1cccc(NC(=N)c2cccs2)c1)OCc1cccc(NC(=N)c2cccs2)c1

InChI Key InChIKey=KEUPBLDQGUHFOB-QHCPKHFHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50023384   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  14.7nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  15nMAssay Description:Inhibition of rat nNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  4.73E+3nMAssay Description:Inhibition of mouse macrophage iNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  4.73E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

US Patent
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  1.67E+4nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

US Patent
LigandPNGBDBM50023384(CHEMBL3325610 | US9242957, QJ-II-203)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of bovine eNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed