BDBM50024605 CHEMBL3330603::US9290463, E
SMILES Cn1c(=O)cnn(CCCCN2CCN(CC2)c2ccccc2)c1=O
InChI Key InChIKey=ZIUFXZSHAGEVLS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50024605
Affinity DataKi: 0.150nM ΔG°: -12.4kcal/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometryMore data for this Ligand-Target Pair