BDBM50030746 CHEMBL3342184::acs.jmedchem.1c00409_ST.413

SMILES CN(Cc1ccccc1)C(=O)CN(NC(=O)OC(C)(C)C)C#N

InChI Key InChIKey=LHJKRUYOLRIDGD-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50030746   

TargetCathepsin D(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  0.00420nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  0.176nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  0.459nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  228nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  1.59E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataIC50:  1.00E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed